77. Involvement of adenosine A1 receptor in the sleep-promoting effect of AR-001 Suyeon Kim, Hye Jin Jee, Ju-Young Park, Eunha Kim*, Sunghou Lee*, Yi-Sook Jung* 2024 Submitted

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76. Bioorthogonal imaging probe for STING protein in live cell and fixed tissue. Heylim Lee,† Juyoung Park,† Jubeen Yoon, Wonjin Park, Gyubin Park, Minseob Koh, Chang Ho Sohn, Sanghee Lee*, Eunha Kim* 2024 In revision

(† These authors equally contributed to this work) 

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75. "Investigation of proteome-tetrazinereactivity discovered3-cyclopropyl-6-phenyl-1,2,4,5-tetrazine as a minimal background biorthogonal click reagent in live cell." Juhee Hahm,† Junyoung Park,† Hwan Min Hwang, Soyeon Lee, Sanghee Lee*, Eunha Kim* Jongmin Park* 2024 in preparation  († These authors equally contributed to this work) 

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74. "Fixative eXchange (FX)-seq: scalable single nucleus RNA sequencing enables profiling oftranscriptomes of heavily PFA-fixed or FFPE mouse and human tissues." Han-Eol Park,† Yu Tak Lee,† Junsuk Lee, Hyelin Ji, Young-Lan Song, Jaewon Lee, Sung-Yon Kim, Junho K. Hur, Eunha Kim, Chung Whan Lee, Yoon Dae Han, Hyunki Kim, and Chang Ho Soh* 2024 In revision. († These authors equally contributed to this work) 

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73. "All-in-one organic ligand for emitting perovskite nanocrystals: Efficient dispersion, photocurable and charge transporting capability" Na Young Cho, Ji Won Jang, Byeong M. Oh, Gyeong Eun Seok, Haewoon Seo, Sang-Wook Kim, Jincheol Kim, Eunsu Kim, Eunha Kim, Hyosung Choi, Bo Ram Lee, Jin Woo Choi*, Jong H. Kim*. Chem. Eng. J. 2024, 485, 149792. DOI: 10.1016/j.cej.2024.149792

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72. In-situ wound healing by SDF-1-mimic peptide-loaded click crosslinked hyaluronic acid scaffold. Young Hun Kim; Shina Kim; Min Ji Han; Hyun Jin Ju; Yongdoo Park; Eunha Kim; Hak Soo Choi; Sangdun Choi, Moonsuk Kim*. J. Control. Release 2023, 364, 420-434. DOI:10.1016/j.jconrel.2023.10.047

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71. Microtubule-destabilizing agents enhance STING-mediated innate immune response via biased mechanism in human monocyte cells. Songhyun Lim, Hee Ra Jung, Hyelim Lee, Yeonjeong Chu, Hyejin Kim, Eunha Kim, Sanghee Lee* Biomedicine & Pharmacotherapy 2023, 169, 115883. DOI:10.1016/j.biopha.2023.115883

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70. "Pure-Water-Soluble Colorimetric Chemosensors for Highly Sensitive and Rapid Detection of Hydrogen Sulfide: Applications to Evaluation of On-Site Water Quality and Real-Time Gas Sensors" H.W. Chun,† J. Zheng,† E.H. Lee, B. M. Oh, C.-B. Lee, J.S. Min, E. Kim, W. Lee, J. H. Kim* Sensors and Actuators B: Chemical  2023, 402, 134989. DOI:10.1016/j.snb.2023.134989

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69. "Development of a Novel HDAC inhibitor Exhibiting Therapeutic Potential to Prevent Depression via HDAC11 inhibition in Microglia" Baek, S. Y.; Kim, T.; Lee, H.; Lee, J.; Choi, H.-S.; Koh, M.; Kim, E.; Jung, M. E.; Iliopoulos, D.; Lee, J.-Y.; Kim, J.*; Lee, S.* Biomedicine & Pharmacotherapy 2023 DOI: 10.1016/j.biopha.2023.115312

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68. "Redirection of CAR-T cell cytotoxicity using metabolic glycan labeling with unnatural sugars" Cha, J. H.†; Kim, E.†; Lee, J.; Kim, E.*; Kim, C.H.*​ J. Med. Chem. 2023, 66, 12, 7804–7812. DOI: 10.1021/acs.jmedchem.3c00048

​

67. "Indolizine-based fluorescent compounds array for noninvasive monitoring of glucose in bio-fluids using on-device machine learning" Kim, H.†; Lee, S.†; Lee, K. W.; Ko, J.*; Yoon, H. C.*; Kim, E.* Dyes and Pigments 2023, 215, 111287. DOI: 10.1016/j.dyepig.2023.111287   († These authors equally contributed to this work) 

 

66. "Synthesis of 1-(5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl)-2-morpholinoethane-1,2-dione Analogues and their Inhibitory Activities with Reduced Cytotoxicity in Lipopolysaccharide-Induced BV2 Cells" Yoon, S.-H.; Cho, D.-Y.; Han, J.-H.; Cho, D.-K.; Kim, E.; Park, J.-Y.*​ Bioorganic & Medicinal Chemistry Letters 79, 129061, 2023, DOI: 10.1016/j.bmcl.2022.129061

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65. "N4-phenylquinazoline-4,6-diamine as a tunable fluorescent scaffold for the development of fluorescent probes" Lee, J.†;  Aslam, A.†; Choi, S.†; Lim, W.; Jung Y. M.; Yoo, H. S.; Park, J. H.; Lee, S.; Kim, E.*; Park, J.* Dyes and Pigments 2023, 210, 110987. DOI:10.1016/j.dyepig.2022.110987 († These authors equally contributed to this work) 

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64. "Self-assembled hyaluronic acid nanomedicine as a topical therapeutic agent for targeted modulation of dysregulated skin barrier and immune responses in a mouse model of psoriasis" Lee, W. H.; Rho, J. G.; Yang, Y. Y.; Lee, S.; Kweon, S.; Kim, H.-M.; Yoon, J.; Choi, H.; Kim, S. H.; You, S.; Song, Y.; Oh, Y. S.; Kim, H.; Han, H. S.; Han, J. H.; Jung, M.; Park, Y. H.; Choi, Y. S.; Han, S.; Lee, J.; Choi, S.; Kim, J.-W.; Park, J. H.; Lee, E. K.; Song, W. K.; Kim, E.*; Kim, W.*​ ACS Nano 16, 12, 20057-20074. 2022, DOI: 10.1021/acsnano.2c07843

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63. "­Single-molecule sensing of an anticancer therapeutic protein-protein interactions using the chemically modified OmpG nanopore" Hwang, H.-J.‡; Kim, J.-S.‡; Lee, J.; Min, J.S.; Kim, E.*; Lee, M.-K.*; Chi, S.-W.* Analytical Chemistry 2022 94, 21, 7449-7454. († These authors equally contributed to this work) 

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62. "Synthesis and biological evaluation of aripiprazole derivatives as potential antituberculosis agents." Reddy, B. R.*;  Gajulapalli, V. P. R., Krishna, V. S.; Sriram, D.; Babu, K. S.; Kim, E.* Results in Chemistry 2022, 4, 100295. DOI: 10.1016/j.rechem.2022.100295

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61. "Harnessing aggregation-induced emission property of indolizine derivative as a fluorogenic bioprobe for endoplasmic reticulum” Arun, V.; Choi, S.; Choi, J.*; Kim, J.*; Kim, E.* Dyes and Pigments 2022, 200, 110118. DOI:10.1016/j.dyepig.2022.110118

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60. "Recent trends in molecular aggregates: a path to explore bio-medicine" Heo, J.; Murale, D. P.; Yoon, H. Y.; Arun, V.; Choi, S.; Kim, E.*; Lee, J.-S.*; Kim, S.* Aggregate 2022, 3, e159. DOI:10.1002/agt2.159

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59. "Development of small-molecule STING activator for cancer immunotherapy" Jung, H. R.; Jo, S.; Jeon, M. J.; Lee, H.; Chu, Y.; Lee, J.; Kim, E.; Jung, C.; Kim, H.*; Lee, S.* Biomedicines 2022, 10(1), 33. DOI: 10.3390/biomedicines10010033

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58. "Fluorescent materials for monitoring mitochondrial biology" " Chu, Y.; Park, J.; Kim, E.*; Lee, S.* Materials 2021, 14(15), 4180. DOI: 10.3390/ma14154180

​

Special Issue "Biomaterials and Molecular Imaging Materials for Biomedical Research"

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57. "Highly Sensitive, Selective, and Rapid Response Colorimetric Chemosensor for Naked Eye Detection of Hydrogen Sulfide Gas under Versatile Conditions: Solution, Thin-Film, and Wearable Fabric" Zheng, J.; Noh, H. L.; Chun, H. W.; Oh, B. M.; Lee, J.; Choi, S.-K.; Kim, E.; Jung, D.; Lee, W. S.; Kim, J. H.* Sensors and Actuators B: Chemical 2021, 341, 130013.

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56. "Overview of Syntheses and Molecular‐Design Strategies for Tetrazine‐Based Fluorogenic Probes." Choi, S.-K.; Kim, J.*; Kim, E.* Molecules, 2021 26(7), 1868. DOI: 10.3390/molecules26071868.

 

Special issue "Tetrazines: A World of New Molecules Emerging from Old Chemistry"

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55. Synthesis and Biological Evaluation of Salicylic Acid Analogues of Celecoxib as a New Class of Selective Cyclooxygenase-1 Inhibitor. Yoon, S.-H.; Cho, D.-Y.; Choi, S.-Y.; Lee, J. -Y.; Choi, D.-K.; Kim, E.; Park, J.-Y.* Biological and pharmaceutical Bulletin 2021, 44(9), 1230-1238. DOI:10.1248/bpb.b20-00991

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54. "A Tetrazine fused-aggregation induced emission luminogen for bioorthogonal fluorogenic molecular bioimaging." Choi, S.; Choi, S.; Lee. Y.; Lee, S.; Kim, W.; Kim, E* Sensors and Actuators B: Chemical  2021, 340, 129966. DOI:10.1016/j.snb.2021.129966.

53. "Fluorescent sensor array for high-precision pH discrimination with mobile-device readout assisted by machine learning." Kim, H.†; Lee, S.†; Min, J.S.; Kim, E.; Ko, J.*; Kim, E* Dyes and Pigments 2021, 193, 109492. DOI: 10.1016/j.dyepig.2021.109492

(† These authors equally contributed to this work) 

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52. "Self-Assembled Hyaluronic Acid Nanoparticles for Osteoarthritis Treatment”, Kang, L.-J.; Yoon, J.; Han, H. S.; Lee, S.; Kim, E.; Kim, S. J.; Lim, T.; Park, J. H.; Yang, S.; Kim, W., Biomaterials 2021, 275, 120967  DOI: 10.1016/j.biomaterials.2021.120967

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51. "A small molecule interferon inducer for cancer immunotherapy targeting non T cell inflamed tumors" Kim, E.; Lee, S.* Journal of Cancer Immunology 2021, 3(1), 13

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50. "Fluorescent Fluoride Sensor Based on Indolizine Core Skeleton for Bioimaging." Kim, H.; Shin, M.; Kim, E.* Bull. Kor. Chem. Soc. 2021 42 (1), 95-98. DOI: 10.1002/bkcs.12134

• Invited article. Special issue "Chemosensor and Imaging probes"

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49. "Synthesis of 4-(3-Oxo-3-phenylpropyl)morpholin-4-ium Chloride Analogues and their Inhibitory Activities of Nitric Oxide Production in Lipopolysaccharide-Induced BV2 Cells" Yoon, S.-H.; Lee, E.; Cho, D.-Y.; Ko H. M.; Baek, H. Y.; Choi, D.-K.; Kim, E.; Park, J.-Y.* Bioorg. Med. Chem. Lett. 2021, 36, 127780.  DOI:10.1016/j.bmcl.2021.127780

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48. "In vivo vocal fold augmentation using an injectable polyethylene glycol hydrogel based on click chemistry" Kwon, S.; Choi, H.; Park, C.; Choi, S.; Kim, E.; Kim, S. W.; Kim, C.-S.; Koo, H.* Biomaterials Science 2021, 9, 108-115.

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47.  "VOCkit: A Low-Cost IoT Sensing Platform for Volatile Organic Compound Classification" Ahn, J.; Kim, H.; Kim, E.*; Ko. J.* Ad Hoc Networks 2021, 113(15), 102360

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46. "Kaleidoscopic fluorescent arrays for high-multiplexed point-of-care chemical sensing" Kim, H.†; Choi, S.-K.†; Ahn, J.†; Yu, H.; Min, K.; Hong, C.; Shin, I.-S.; Lee, S.; Lee, H.; Im, H.*; Ko, J.*; Kim, E.* Sensors and Actuators B: Chemical 2021, 329, 129248. († These authors equally contributed to this work) DOI: 10.1016/j.snb.2020.129248

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45.  "Design, synthesis, and biological evaluation of N-arylpiperazine derivatives as interferon inducers" Chu, Y.†; Gajulapalli, V. P. R.†; Kim, E.*; Lee, S*.  Bioorgnic and Medicinal Chhemistry Letter 2020, 30(24), 127613.  DOI:10.1016/j.bmcl.2020.127613

(† These authors equally contributed to this work)

​

44. "Full Color Tunable Aggregation-Induced Emission Luminogen for Bioimaging Based on an Indolizine Molecular Framework" Choi, S.-K.; Rho, J.; Yoon, S. E.; Yoon, W.; Kim, J.; Yun, H.; Kim, W.; Kim, E.* Bioconjugate Chemistry. 2020, 31(11), 2522-2532. DOI: 10.1021/acs.bioconjuchem.0c00467 

• Cover article

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43. A Novel small-molecule inhibitor of endosomal TLRs reduces inflammation and alleviates autoimmune disease symptoms in murine models. Patra, M. C.; Achek, A.; Panneerselvam, S.; Shin, H.-J.; Baek, W.-Y.; Lee, W. H.; Sung, J.; Cho, E.-Y.; Kim, G.-Y.; Kim, W.; Kim, E.; Suh, C.-H.; Choi, S.* 2020 Cells 9(7), E1648. DOI:10.3390/cells9071648 PMID: 32660060

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42. Near-infrared light-triggered photodynamic therapy and immune response using upconversion nanoparticles with dual photosensitizers. Lee, S. Y.; Lee, R.; Kim, E.; Lee, S.*; Park, Y. I.* Frontiers in Bioengineering and Biotechnology 2020 DOI:10.3389/fbioe.2020.00275. PMID: 32373598

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41. A Dodecapeptide Selected by Phage Display as a Potential Theranostic Probe for Colon Cancers. Kwak, M.H.; Yi, G.; Yang, S. M.; Choe, Y.; Choi, S.; Kim, E.; Na, K.; Choi, M.-G.; Koo, H.; Park, J. M.* 2020 Translational Oncology 13(9), 100798. DOI: 10.1016/j.tranon.2020.100798. PMID: 32454443

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40. Intravital longitudinal imaging of hepatic lipid droplet accumulation in a murine model for nonalcoholic steatohepatitis. Moon, J.; Kong, E.; Lee, J.; Jung, J.; Kim, E.; Park, S. B.; Kim, P.* Biomedical Optics Express 2020, 11, 5132-5146  

• Editor's Pick

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39. Click chemistry-mediated tumor-targeting of SN38-loaded nanoparticles using trastuzumab. Yoo, J.; Choi, S.; Son, J.; Yi, G.; Kim, E.; Koo, H.* Biochem. Biophys. Res. Commun 2019, 515(1), 207-213. DOI: 10.1016/j.bbrc.2019.05.128. PMID:31146921

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38. Development of Azo-Based Turn-On Chemical Array System for Hydrazine Detection with Fluorescence Pattern Analysis. Shin, M. C.†; Lee, Y.†; Park, S. B.*; Kim, E.* ACS Omega 2019, 4(12), 14875–14885. DOI:10.1021/acsomega.9b01487, PMC6751537 

(† These authors equallycontributed to this work) 

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37. Development of theragnostic tool using Near-IR fluorescent probe targeting mitochondria in brain tumor. Chu, Y.; Shin, M. C.; Sung, J.; Park, J.; Kim, E.*; Lee, S.* Bioconjugate Chem. 2019, doi.org/10.1021/acs.bioconjchem.9b00375

 

36. "Designing a Low-Cost IoT Sensing Platform for VOC Material Classification." Ahn, J.; Kim, H.; Kim, E.; Ko, J. IEEE DCOSS 2019, 8, 82-89.

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35. Biomedical applications of copper-free click chemistry: in vitro, in vivo and ex vivo. Kim, E.; Koo, H.* Chemical Science 2019, 10, 7835-7851. DOI: 10.1039/c9sc03368h 

• Cover article. 

• Most popular 2019-2020 review articles, 

• Most popular 2019-2020 chemical biology articles

• Celebrating Chemical Science in Korea

• Most popular 2018-2019 review articles

• Most popular 2018-2019 chemical biology articles

 

34. "A new-infrared probe targeting mitochondria via regulation of molecular hydrophobicity." Sung, J.†; Rho, J. G.†; Jeon, G. G.; Chu, Y.; Min, J. S.; Lee, S.; Kim, J. H.; Kim, W.*; Kim, E.* Bioconjugate Chem. 2019, 30, 210-217. († These authors equally contributed to this work)

• ACS Editors' Choice

 

33. "Template-Free anion-controlled synthesis of Pd(II) nano-aggregates for the Antifouling Polymerization of CO and Ethylene." Lim, Y.-N.; Chae, S. K.; Yim, W.; Park, J.; Kim, E.; Son, S. U.*; Jang, H.-Y.* Appl. Organomet. Chem. 2019,  DOI: https://doi.org/10.1002/aoc.4761

 

32. "Volatile Organic Compounds Recognition Using a Smartphone Camera and Fluorometric Sensors." Ahn, J.; Kim, H.; Kim, E.; Ko, J. Workshop on Combining Physical and Data-driven Knowledge in Ubiquitous Computing

(Co-located with ACM Ubicomp) 2018 Singapore. - Conference and Workshop Proceeding

 

31. "Near infrared fluorescent tracer for glucose uptake monitoring in live cell." Jo, A.†; Sung, J.†; Lee, S.; Nam, S.; Lee, H. W.; Park, J.; Kim, H.; Kim, E.*; Park, S. B.*  Bioconjugate Chem 2018, 29, 3394-3401. († These authors equally contributed to this work) DOI: 10.1021/acs.bioconjchem.8b00558, PMID:30183256

 

30. "Multiplexed Profiling of Single Extracellular Vesicles" Lee, K.†; Fraser, K.†; Ghaddar, B.; Yang, K.; Kim, E.; Balaj, L.; Chiocca, E. A.; Breakefield, X. O.; Lee, H.*; Weissleder, R.* ACS Nano 2018, 12(1), 494-503. DOI:10.1021/acsnano.7b07060. († These authors equally contributed to this work)

 

29. "Mono-chromophore Design Strategy for Tetrazine-based Colorful Bioorthogonal Probes with a Single Fluorescent Core Skeleton" Lee, Y.; Cho, W.; Sung, J.; Kim, E.*; Park, S. B.*  J. Am. Chem. Soc., 2018, 140(3), 974-983. DOI: 10.1021/jacs.7b10433. 

• Cover article

 

28. "Near infrared imaging of Mer tyrosine kinase (MerTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease." Miller, M. A.; Kim, E.; Cuccarese, M. F.; Plotkin, A. L.; Prytyskach, M.; Kohler, R. H.; Pittet, M.; Weissleder, R.*  Chem. Commun., 2018, 54, 42–45. DOI: 10.1039/C7CC07581B

 

27. "Neuron-Material Nanointerfaces: Surface Nanotopography Governs Neuronal Differentiation and Development" Kim, H. K.; Kim, E.; Kim. Y.-K.; Kang, K.* ChemNanoMat, 2017, 3, 278–287. DOI: 10.1002/cnma.201700063.

 

26. "Tetrazine ligation for chemical proteomics " Kang, K.; Park, J.*; Kim, E.* Proteome Science 2017, 15, 15. DOI : 10.1186/s12953-017-0121-5.

 

25. "Development of fluorescent mitochondria probe based on 1,2-dihydropyrrolo[3,4-b]indolizine-3-one " Sung, J.; Lee, Y.; Cha, J. H.; Park, S. B.*, Kim, E.* Dyes and Pigments 2017, DOI : 10.1016/j.dyepig.2017.06.014 .

 

24. "Facile coating strategy to functionalize inorganic nanoparticles for biosensing" Park, Y. I.; Kim, E.; Huang, C.-H.; Park, K. S.; Castro, C.; Lee, H.*; Weissleder, R.* Bioconjugate Chem. 2017, 28, 33-37.  PMID : 27792877

 

23. "Quantitating drug-target engagement in single cells in vitro and in vivo." Dubach, J. M.; Kim, E.; Yang, K.; Cuccarese, M.; Giedt, R.; Meimetis, L. G.; Vinegoni C.*; Weissleder, R.* Nat. Chem. Biol. 2017, 13, 168-173. PMID: 27918558

 

22. "Replacement of dialkyl amino group on D-A type fluorophores to increase brightness" Kim, E.* Bull. Kor. Chem. Soc.  2016, 37, 1741-1742. Cover article. 

 

21. "High-content screening platform with fluorescent chemical probes for discovery of first-in-class therapeutics" Jo, A.; Jung, J.; Kim, E.; Park , S. B.* Chem. Commun. 2016, 52, 7433-7445. PMID : 27166145

 

 

20. "Bioorthogonal click chemistry enables synthetic cell-cell adhesion." Koo, H.; Choi, M.; Kim, E.; Hahn, S. K.; Weissleder, R.; Yun, S. -H.* Small, 2015, 11, 6458-6466. PMID : 26768353 Featured as ‘Frontispiece’ in Small.  

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